West Pier will look to make it a hat-trick of wins over rivals Newlands on Saturday.
Andy Spivey's side have beaten Newlands twice already this season, and the rivals meet at Sherburn in the District Cup this weekend.
The club's respective Sunday sides also do battle the next morning in the Kenward Cup in the pick of the Sunday League clashes.
Hunmanby United v Edgehill, West Pier v Newlands, Whitby Fishermen v Filey Town, Sleights v Seamer.
Seamer Reserves v Goalsports, Ayton v Kirkbymoorside Reserves, Edgehill Reserves v Sherburn, Ryedale SC v Filey Town Reserves, Kirkdale United v Goldsborough United, Heslerton v Newlands Reserves
Frank White Trophy (1.30)
Scalby Reserves v Itis Itis Rovers
Division One (2pm)
Cayton v Westover
Division Two (2pm)
Falsgrave v Cayton Reserves, Duchess v Snainton, West Pier Reserves v Scalby
Division Three (2pm)
Commercial v Westover Reserves, Fishburn Park Reserves v Eastway, Goalsports Reserves v Seamer 3rds, Edgehill 3rds v Hunmanby United Reserves
Kenward Cup (10.30am)
Heslerton v Cayton, Newlands Reserves v FILO, Roscoes Bar v Scalby, Trafalgar v Fylingdales, West Pier v Newlands
Division Two (10.30am)
Angel v Fylingdales Reserves, Crown Tavern v Ayton Reserves