Thom Yorke – famous for such hits as Karma Police, Creep, No Surprises and Paranoid Android – will walk with around 200 other campaigners who are expected to take part in the demonstration against the upgrading of the radar at Fylingdales for the purposes of American missile defence.
The rally takes place near the slip road to Ellerbeck from noon on Saturday and will include an information stall, marquee and speeches from Thom as well as Campaign for Nuclear Disarmament chairwoman Kate Hudson and Green Party MEP Caroline Lucas.
People from all over the world will be taking part in similar protests against the early warning missile defence which the US wants to install to enable rockets from Russia, China or the Middle East to be spotted early so they can be intercepted.
Defence Secretary Geoff Hoon has said he believes the plans will not change the threat of an attack on the Fylingdales base, but opponents say the scheme would make the UK a target.
Jackie Fearnley, of Goathland, strongly believes the upgrade should not take place.
"The upgrade has already started so it would be easy to give up, but I think it is important to keep up our resistance to this project," she said.
"A lot of people think it is so far-fetched it is not worth worrying about, but it is really happening and it is important to try and get as much information as we can.
"The so-called "Son of Star Wars" project will have a dangerously destablising effect on international relations, enhancing America's perception of its invincibility and making it more likely than ever that they would countenance first strikers on other countries.
"We are told that the stage is a simple computer upgrade, but all the while changes in the balance of power are occurring.
"We don't want to find ourselves 10 years ahead looking back guiltily wondering how we allowed international relationships to be completely dominated by America or our citizenry to be under a system of surveillance and control that undermined all our hard-won freedoms."
Mrs Fearnley said Thom Yorke is very keen on the campaign and has been wearing a Star Wars t-shirt at all of his gigs.
"Hopefully he will bring in the next generation," she said.